Contrasting BioCryst Pharmaceuticals (NASDAQ:BCRX) and Erytech Pharma (NASDAQ:ERYP)

BioCryst Pharmaceuticals (NASDAQ:BCRX) and Erytech Pharma (NASDAQ:ERYP) are both small-cap medical companies, but which is the better investment? We will compare the two companies based on the strength of their institutional ownership, valuation, risk, analyst recommendations, earnings, dividends and profitability.


This table compares BioCryst Pharmaceuticals and Erytech Pharma’s net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
BioCryst Pharmaceuticals -472.12% -223.34% -71.72%
Erytech Pharma N/A N/A N/A

Analyst Recommendations

This is a breakdown of recent ratings and target prices for BioCryst Pharmaceuticals and Erytech Pharma, as reported by

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
BioCryst Pharmaceuticals 0 4 5 0 2.56
Erytech Pharma 0 0 1 0 3.00

BioCryst Pharmaceuticals presently has a consensus target price of $9.64, indicating a potential upside of 184.45%. Given BioCryst Pharmaceuticals’ higher possible upside, equities research analysts plainly believe BioCryst Pharmaceuticals is more favorable than Erytech Pharma.

Risk & Volatility

BioCryst Pharmaceuticals has a beta of 2.14, indicating that its stock price is 114% more volatile than the S&P 500. Comparatively, Erytech Pharma has a beta of 1.54, indicating that its stock price is 54% more volatile than the S&P 500.

Institutional & Insider Ownership

92.0% of BioCryst Pharmaceuticals shares are owned by institutional investors. Comparatively, 8.2% of Erytech Pharma shares are owned by institutional investors. 5.2% of BioCryst Pharmaceuticals shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company will outperform the market over the long term.

Earnings & Valuation

This table compares BioCryst Pharmaceuticals and Erytech Pharma’s revenue, earnings per share and valuation.

Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio
BioCryst Pharmaceuticals $20.65 million 18.11 -$101.25 million ($0.98) -3.46
Erytech Pharma N/A N/A -$45.14 million $2.44 2.84

Erytech Pharma has lower revenue, but higher earnings than BioCryst Pharmaceuticals. BioCryst Pharmaceuticals is trading at a lower price-to-earnings ratio than Erytech Pharma, indicating that it is currently the more affordable of the two stocks.


Erytech Pharma beats BioCryst Pharmaceuticals on 7 of the 13 factors compared between the two stocks.

About BioCryst Pharmaceuticals

BioCryst Pharmaceuticals, Inc., a biotechnology company, discovers oral and small-molecule medicines. The company markets peramivir injection, an intravenous neuraminidase inhibitor, for the treatment of acute uncomplicated influenza under the RAPIVAB, ALPIVAB, RAPIACTA, and PERAMIFLU names; and Mundesine, an oral purine nucleoside phosphorylase inhibitor for peripheral T-cell lymphoma. It is also developing BCX7353, an oral serine protease inhibitor and oral dose formulation that is in Phase III clinical trials to treat hereditary angioedema; BCX9930, an oral factor D inhibitor, which is in Phase I clinical trials for mediated diseases; BCX9250, an oral activin receptor-like kinase-2 inhibitors that is in preclinical trials to treat fibrodysplasia ossificans progressive; and Galidesivir, an RNA dependent-RNA polymerase inhibitor, which is in Phase I clinical trials to treat various RNA viruses, including Marburg, Yellow Fever, Ebola, and Zika. The company has collaborations and in-license relationships with U.S. Department of Health and Human Services; National Institute of Allergy and Infectious Diseases; Seqirus UK Limited; Shionogi & Co., Ltd.; Green Cross Corporation; Mundipharma International Holdings Limited; and The University of Alabama at Birmingham, as well as Albert Einstein College of Medicine of Yeshiva University and Industrial Research, Ltd. BioCryst Pharmaceuticals, Inc. was founded in 1986 and is headquartered in Durham, North Carolina.

About Erytech Pharma

ERYTECH Pharma S.A., a biopharmaceutical company, develops therapies for severe forms of cancer and orphan diseases. It is developing a pipeline of product candidates targeting solid and liquid tumors for patients with high unmet medical needs. The company's lead product candidate is eryaspase, which is used for the treatment of severe solid tumors, including pancreatic cancer and in acute lymphoblastic leukemia. It is preparing for the launch of a pivotal Phase III clinical trial of eryaspase in the United States and Europe. ERYTECH Pharma S.A. has research collaborations with the Fox Chase Cancer Center to advance the preclinical development of erymethionase for the treatment of homocystinuria and with Queen's University of Canada to advance the preclinical development of eryminase for the treatment of arginase-1-deficiency. ERYTECH Pharma S.A. was founded in 2004 and is based in Lyon, France.

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