Analyzing Proteon Therapeutics (NASDAQ:PRTO) & Moderna (NASDAQ:MRNA)

Proteon Therapeutics (NASDAQ:PRTO) and Moderna (NASDAQ:MRNA) are both medical companies, but which is the better stock? We will contrast the two businesses based on the strength of their risk, dividends, earnings, profitability, analyst recommendations, institutional ownership and valuation.

Valuation and Earnings

This table compares Proteon Therapeutics and Moderna’s top-line revenue, earnings per share (EPS) and valuation.

Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio
Proteon Therapeutics N/A N/A -$20.73 million ($1.15) -0.22
Moderna $135.07 million 34.36 -$384.73 million ($4.95) -2.84

Proteon Therapeutics has higher earnings, but lower revenue than Moderna. Moderna is trading at a lower price-to-earnings ratio than Proteon Therapeutics, indicating that it is currently the more affordable of the two stocks.


This table compares Proteon Therapeutics and Moderna’s net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
Proteon Therapeutics N/A N/A -107.30%
Moderna N/A N/A N/A

Insider and Institutional Ownership

24.0% of Proteon Therapeutics shares are held by institutional investors. Comparatively, 43.2% of Moderna shares are held by institutional investors. 45.7% of Proteon Therapeutics shares are held by insiders. Comparatively, 34.5% of Moderna shares are held by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock is poised for long-term growth.

Analyst Recommendations

This is a breakdown of current ratings and recommmendations for Proteon Therapeutics and Moderna, as provided by

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Proteon Therapeutics 0 4 1 0 2.20
Moderna 0 0 9 0 3.00

Proteon Therapeutics presently has a consensus target price of $3.33, indicating a potential upside of 1,213.89%. Moderna has a consensus target price of $27.56, indicating a potential upside of 96.06%. Given Proteon Therapeutics’ higher probable upside, equities research analysts plainly believe Proteon Therapeutics is more favorable than Moderna.

Proteon Therapeutics Company Profile

Proteon Therapeutics, Inc., a late-stage biopharmaceutical company, focuses on the development of pharmaceuticals to address the needs of patients with renal and vascular disease. Its lead product candidate is vonapanitase, an investigational drug intended to enhance hemodialysis vascular access outcomes. The company develops vonapanitase, a recombinant human elastase, which has completed Phase II and Phase III clinical trials for patients with chronic kidney disease. It is also evaluating vonapanitase in a Phase I clinical trial in patients with peripheral artery disease. The company was founded in 2001 and is based in Waltham, Massachusetts.

Moderna Company Profile

Moderna, Inc., a clinical stage biotechnology company, develops therapeutics and vaccines based on messenger RNA for the treatment of infectious diseases, immuno-oncology, rare diseases, and cardiovascular diseases. As of February 15, 2019 the company had 11 programs in clinical trials and a total of 20 development candidates in six modalities comprising prophylactic vaccines, cancer vaccines, intratumoral immuno-oncology, localized regenerative therapeutics, systemic secreted therapeutics, and systemic intracellular therapeutics. It has strategic alliances with AstraZeneca, Merck & Co., Vertex Pharmaceuticals, Biomedical Advanced Research and Development Authority, Defense Advanced Research Projects Agency, and Bill & Melinda Gates Foundation. The company was formerly known as Moderna Therapeutics, Inc. and changed its name to Moderna, Inc. in August 2018. Moderna, Inc. was founded in 2010 and is headquartered in Cambridge, Massachusetts.

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